OMNICON, OMNICON Zones of Inhibition System, OMNICON Zone Reader, OMNICON Image Analysis System, OMNICON Image Analyzer, Zones Reader, Automated Zone Reader, Automatic Zones Reader, Zones of Inhibition, Inhibition Zone, Agar Diffusion, Agar Diffusion Assay, Antibiotic Potency Testing, Antibiotic Testing, Potency Testing, USP 24, CFR 21, British Pharmacopoeia, BP, European Pharmacopoeia, EP, Large Plate, Latin Square, Nystatin, Mycostatin, Gentamycin, Erythromycin, Polymixin, Amoxicillin, Bacitracin, Vancomycin

Zones of Inhibition
United States Pharmacopoeia / CFR Method

Calculations

Performs all calculations in accordance to the procedures defined in the Code of Federal Regulations Standard (CFR) 436.105 as well as in the Section of Design and Analysis of Biological Assays <111>, Chapter of Biological Tests, United States Pharmacopoeia (USP) XXIV. The software calculates the mean and standard deviation values, excludes zones based on the USP Outlier Test and draws the Zones of Inhibition potency line graph for the Standard Analysis. It also calculates the differences between the reference assay and the sample test assay; obtain the mean and standard deviation of these differences, calculate the label claim percentage and the determined potency value for the Trial Analysis, or the Trial analysis results based on weight and dilution.

Plate Reading

The OMNICON Zones Reader reads each 100 mm petri dish in less than 2 seconds, measuring the diameter and shape of the zone. The shape value is used to exclude zones which are oval due to spills or irregular growth.